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Tietoja antroposofisesta lääketieteestä
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Antroposofinen lääketiede:
vaikuttavuus, käyttö, kustannukset, turvallisuus
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Facts and Figures Anthroposophic Medicine
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Antroposofinen lääketiede EU:ssa

CAMDOC
www.camdoc.eu

EUROCAM
www.cam-europe.eu

CAM-Interest Group meetings in the European Paliament
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CAM-seminaarit EU-Parlamenttissa
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CAMbrella: www.cambrella.eu
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Sivukartta

Tutkimusjulkaisut Antroposofisen lääketieteen alalla

Tuoreimmat tutkimustulokset

Effects of live music therapy on heart rate variability and selfreported stress and anxiety among hospitalized pregnant women: A randomized controlled trial. Teckenberg-Jansson P, Turunen S, Pölkki T, Lauri-Haikala M-J, Lipsanen J, Henelius A, Aitokallio-Tallberg A, Pakarinen S, Leinikka M and Huotilainen M. Nordic Journal of Music Therapy 2019, 28:1, 7-26. DOI: 10.1080/08098131.2018.1546223

Do NHS GP surgeries employing GPs additionally trained in integrative or complementary medicine have lower
antibiotic prescribing rates? Retrospective cross-sectional analysis of national primary care prescribing data in England in 2016. van der Werf ET, Duncan LJ, Flotow P, et al. BMJ Open 2018;8:e020488. doi:10.1136/ bmjopen-2017-020488. Open access

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access

An assessment of the scientific status of anthroposophic medicine, applying criteria from the philosophy of science. Baars EW, Kiene H, Kienle GS, Heusser P, Hamre HJ. Complementary Therapies in Medicine Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.04.010 Open access

Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters. Rentsch G, Steinborn C, Klemd AM, Kienle GS, Gründemann C, Huber R. . Complementary Therapies in Medicine 2018;40:133-144.

Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text

Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text

The Subjective Dimension of Integrative Cancer Care: A Qualitative Study Exploring the Perspectives, Themes, and Observations of Experienced Doctors from the Area of Anthroposophic Medicine. Kienle GS, Mussler M, Fuchs D, Kiene H: Explore 2018; 14:342-351 Full text

Inverse relationship between reduced fatigue and severity of anemia in oncology patients treated with integrative medicine: understanding the paradox. Ben-Arye E, Dahan O, Shalom-Sharabi I, Samuels N (2018) Supportive Care in Cancer. 10 pp. DOI: 10.1007/s00520-018-4271-5

The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Park JB, Lee SA, Lee WS, Kim YH, Hwang JJ (2018) The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Journal of Thoracic Disease 10 (1), 371-376. Read more

Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings. Von Bonin D, Klein SD, Würker, Streit E, Avianus O, Grah C, Salomon J and Wolf Ucorresponding author. BioMedCentral. Published online 2018 Jun 25. doi: 10.1186/s13063-018-2727-z. Open access

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis.Schad F, Thronick e A, Steele ML, Merkle A, Matthes B, Grah C, et al. (2018). PLoS ONE 13(8): e0203058. Open access

Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access

Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access

On Caring and Sharing--Addressing Psychological, Biographical, and Spiritual Aspects in Integrative Cancer Care: A Qualitative Interview Study on Physicians’ Perspectives. Complementary Therapies in Medicine. Kienle GS, Mussler M, Fuchs D, Kiene H. May 2018. https://doi.org/10.1016/j.ctim.2018.04.012

Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters. Steinborn C, Rentsch G, Klemd AM, Kienle GS, Gründemann C. Complementary Therapies in Medicine, 2018 Volume 40, October 2018, Pages 133-144 Read more

An assessment of the scientific status of anthroposophic medicine, applying criteria from the philosophy of science. Baars EW Helmut Kiene H, Kienle GS, Heusser P, Hamre HJ. Complementary Therapies in Medicine. Volume 40, October 2018, Pages 145-150. Read more

Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more

A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more

Reduction of the frequency of recurrent diverticulitis episodes under treatment with the integrative medicine therapies Carpellum Mali comp. and Kalium aceticum comp. - A case report. Meyer R, Werthmann PG, Kienle GS. Complementary Therapies in Medicine. Volume 40, October 2018, Pages 203-206. Read more

Erfahrungen am Lebensende: Eine Umfrage bei Ärzten und Pflegenden eines Spitals für anthroposophisch erweiterte Medizin. Klein S, Kohler S, Krüerke D, Templeton A, Weibel A, Haraldsson E, Nahm M, Wolf U; Complementary Medicine Research 2018 25:38-43. https://doi.org/10.1159/000478090

A 4-year non-randomized comparative phase–IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference. Hamre H J, Pham Van N, Kern Ch, Rau R, Klasen J, Schendel U, Gerlach L, Drabik A, Simon L; Patient Preference and Adherence 2018 12: 375-97 DOI: https://doi.org/10.2147/PPA.S145221

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronicke A, Li Oei S, Merkle A, Herbstreit C, Lemmens HP, Grah C, Kröz M, Matthes H, Schad F; Complementary Therapies in Medicine 2018 DOI: https://doi.org/10.1159/000478655

Katsaukset

A systematic literature review on the effectiveness of eurythmy therpy. Lötzke D, Heusser P, Büssing A. J Integr Med. 2015 Jul;13(4):217-30. doi: 10.1016/S2095-4964(15)60163-7. http://www.ncbi.nlm.nih.gov/pubmed/25808905

Overview of the Publications From the Anthroposophic Medicine Outcomes Study (AMOS): A Whole System Evaluation Study. Hamre HJ, Kiene H, Ziegler R, Tröger W, Meinecke C, Schnürer C, Vögler H, Glockmann A, Kienle S: Global Adv Health Med. 2014;3(1):54-70. DOI: 10.7453/gahmj.2013.010.
Full article: http://www.gahmj.com/doi/pdf/10.7453/gahmj.2013.010

Anthroposophic Medicine: An Integrative Medical System Originating in Europe. Kienle GS, Albonico H-U, Baars, Hamre HJ, Zimmermann P and Kiene H. Global Adv Health Med. 2013;2(6):20-31. DOI: 10.7453/gahmj.2012.087

Arts Therapies for Anxiety, Depression, and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Boehm K, Cramer H, Staroszynski T and Ostermann T: Hindawi Publishing Corporation. Evidence-Based Complementary and Alternative Medicine.Volume 2014, Article ID 103297, 9 pages http://dx.doi.org/10.1155/2014/103297

Music therapy as part of integrative neonatology: 20 years of experience. Thiel, M.T.; Findeisen, B.; Längler, A. 2011. Music therapy as part of integrative neonatology: 20 years of experience – 3 case reports and a review. Forsch Komplementärmed 18(1): 31–35. doi:10.1159/000323714. https://www.ncbi.nlm.nih.gov/pubmed/21372585

 

Quality of life and related dimensions in cancer patients treated with mistletoe extract, a meta-analysis.

Büssing, A.; Raak, C.; Ostermann, T. 2011. Quality of life and related dimensions in cancer patients treated with mistletoe extract (Iscador): a meta-analysis. Evid Based Complement Alternat Med 2012: 219402. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124023/

Klinische Forschung zur Anthroposophischen Medizin – Update eines «Health Technology Assessment»-Berichts und Status Quo. Kienle GS, Glockmann A, Grugel R, Hamre HJ, Helmut Keine H: Forsch Komplementmed 2011;18:4-4 (DOI: 10.1159/000331812).

Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies. Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.

Clinical research in anthroposophic medicine. Hamre HJ, Kiene H, Kienle GS. Altern Ther Health Med 2009;15(6):52-55.

Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research. Kienle GS, Glockmann A, Schink M and Kiene H: Journal of Experimental & Clinical Cancer Research 2009;28:79.

Survival of cancer patients treated with mistletoe extract (Iscador): a systematic literature review. Ostermann T, Raak C, Büssing A BMC Cancer 2009, 9:451 (pp. 1-9) (http://www.biomedcentral.com/1471-2407/9/451) read more... Comment on Mistletoe therapy in oncology (Cochrane Review 2008) IFAEMM: Kiene, Kienle 2008 read more...

Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extract. Kienle GS, Kiene H. Eur J Med Res 2007;12:103-19.

Anthroposophic Medicine, Effectiveness, utility, costs, safety. Kienle GS, Kiene H, Albonico HU. . Schattauer, Stuttgart, New York, 2006.

Mistletoe in cancer – a systematic review on controlled clinical trials. Kienle GS, Berrino F, Bussing A, Portalupi E, Rosenzweig S, Kiene H. Eur J Med Res 2003;8(3):109-19.

Turvallisuus, antroposofisten lääkevalmisteiden mahdolliset riskit, sivuvaikutukset ja interaktiot

Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access

Use and Safety of Anthroposophic Medicinal Products: An Analysis of 44,662 Patients from the EvaMed Pharmacovigilance Network. Hamre HJ, Glockmann A, Heckenbach K and Matthes H. September 2017. Drugs - Real World Outcomes 4(4):1-15. DOI: 10.1007/s40801-017-0118-5 Open access

Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. Thronicke A, Steele ML, Grah C, Matthes B, Schad F (2017). BMC Complementary and Alternative Medicine 17:534. 10 pp. DOI: 10.1186/s12906-017-2045-0

Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients. Schad F, Thronicke A, Merkle A, Matthes H, Steele ML (2017). Phytomedicine 36, 54-58. DOI: 10.2016/j.phymed.2017.09.004

Safety of intravenously applied mistletoe extract – results from a phase I dose escalation study in patients with advanced cancer. Huber R, Schlodder D, Effertz C, Rieger S, Tröger W (2017). BMC Complementary and Alternative Medicine 17:465. 8 pp. DOI: 10.1185/s12906-017-1971-1

Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities. Schink M, Dehus O (2017). BMC Complemetary and Alternative Medicine 17:521. 8 pp. DOI: 10.1186/s12096-017-2028-1

Use and Safety of Intratumoral Application of European Mistletoe (Viscum album L) Preparations in Oncology. Steele ML, Axtner J, Happe A, Kröz, M, Matthes, H and Schad F. Integr Cancer Ther March 2015 vol. 14 no. 2 140-148. DOI: 10.1177/1534735414563977 ict.sagepub.com.

Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Steele ML, Axtner J, Happe A, Kröz, Matthes and Schad F. Evidence-Based Complementary and Alternative Medicine, 2014; Article ID 236310. Volume 2014,http://dx.doi.org/10.1155/2014/236310

Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. Weissenstein U , Kunz M , Urech K and Baumgartner S. BMC Complementary and Alternative Medicine 2014, 14 :6 Open access: http://www.biomedcentral.com/1472-6882/14/6

Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Steele ML, Axtner J, Happe A, Kröz M, Matthes H and Schad F. Evidence-Based Complementary and Alternative Medicine Volume 2014, Article ID 724258, 11 pages http://dx.doi.org/10.1155/2014/724258

Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2014. Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Dtsch Ärztebl Int 111(29–30): 493–502. doi:10.3238/arztebl.2014.0493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150026/; http://www.aerzteblatt.de/pdf.asp?id=161151

Additional therapy with a mistletoe product during adjuvant chemotherapy of breast cancer patients improves quality of life. Tröger, W.; Ždrale, Z.; Tišma, N.; Matijašević, M. 2014. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evid Based Complement Alternat Med 2014: 430518. doi:10.1155/2014/430518. https://www.hindawi.com/journals/ecam/2014/430518/

Viscum [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2013. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomized clinical trial on overall survival. Eur. J. Cancer 49(18): 3788–3797. https://www.ncbi.nlm.nih.gov/pubmed/23890767; http://www.ejcancer.com/article/S0959-8049%2813%2900550-9/pdf

NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS, Stagl J, Johnson LL, Blackman MR, Grem JL, Swain SM, Monahan BP: Evidence-Based Complementary and Alternative Medicine 2013, 2013: 964592 http://www.hindawi.com/journals/ecam/2013/964592/

Network Oncology (NO) – a Clinical Cancer Register for Health Services Research and the Evaluation of Integrative Therapeutic Interventions in Anthroposophic Medicine. Schad F, Axtner J, Happe A, Breitkreuz T, Paxino C, Gutsch J, Matthes B, Debus M, Kröz M, Spahn G, Riess H, von Laue H and Matthes H. Forsch Komplementmed 2013;20:353–360 Published online: October 24, 2013 DOI: 10.1159/000356204 Accessible online at: www.karger.com/fok

Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with a mistletoe extract to chemotherapy alone. Tröger, W.; Ždrale, Z.; Stanković, N.; Matijašević, M. 2012. Fiveyear follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl) 6: 173–180. doi:10.4137/BCBCR.S10558. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493140/

Anthroposophic medicine in pediatric primary care: a prospective, multicenter observational study on prescribing patterns. Jeschke E, Ostermann T, Tabali M, Kroz M, Bockelbrink A, Witt CM, Willich SN, Matthes H: Altern Ther Health Med 2011;17:18-28.

Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more

The treatment of children with anthroposophic medicine in daily primary care - Results of a network study. Jeschke E, Ostermann T, Tabali M, Bockelbrink A, Witt C, Willich S, Matthes H. European Journal of Integrative Medicine 2009;1(4):203. read more

Prescribing practices in the treatment of upper respiratory tract infections in anthroposophic medicine. Jeschke E, Lueke C, Ostermann T, Tabali M, Huebner J, Matthes H. Forsch Komplementärmed 2007;14:207-15.

QuaDoSta - ein frei konfigurierbares System zur Unterstützung multizentrischer Datenerhebungen in medizinischer Versorgung und Forschung. Jeschke E, Schad F, Pissarek J, Matthes B, Albrecht U, Matthes H. GMS Med Inform Biom Epidemiol 2007;3(2):Doc 10.

Quality of life is improved in breast cancer patients by Standardised Mistletoe Extract PS76A2 during chemotherapy and follow-up: a randomised, placebo-controlled, double-blind, multicentre clinical trial. Semiglasov VF, Stepula VV, Dudov A, Schnitker J, Mengs U: Anticancer Res 2006, 26:1519-1530 http://ar.iiarjournals.org/content/26/2B/1519.full.pdf

Safety of homeopathic injectables for subcutaneous administration: a documentation of the experience of prescribing practitioners.Baars EW, Adriaansen-Tennekes R, Eikmans KJ. J Altern Complement Med 2005;11(4):609-616.

Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Piao BK, Wang YX, Xie GR, Mansmann U, Matthes H, Beuth J, Lin HS: Anticancer Res 2004, 24:303-309 http://ar.iiarjournals.org/content/24/1/303.full.pdf

Kliininen tutkimus aihepiirin mukaan

Allergologia

Allergic disease and sensitization in Steiner school children. Floistrup H, et al. The Parsifal Study Group. J Allergy Clin Immunol. 2006 Jan;117(1):59-66. Epub 2005 Nov 28.

Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G. Lancet. 1999 May 1;353(9163):1485-8. (1999)

Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.

Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.

Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.

An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.

Endokrinologia

Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism.
Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/

Gastroenterologia

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T,  Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019

Geriatria

Anthroposophy and Integrative Care at the End of Life. Ciro Augusto Floriani CA. Alternative and complementary therapies. 2016; 22(3): DOI: 10.1089/act.2016.29055.caf http://online.liebertpub.com/doi/abs/10.1089/act.2016.29055.caf

Usage of Complementary and Alternative Medicine Interventions by German Older Adults. Büssing A, Ostermann T, Heusser P, Matthiessen PF: J Altern Complement Med. 2011; 17(6):487-489

Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study. Jeschke E, Ostermann T, Vollmar HC, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H. BMC Geriatrics 2010, 10:48. read more...

The self regulation questionnaire as a measure in quality of life research.Büssing A, Girke M, Heckmann C, Matthiesen P, Schad F, Ostermann T, Kröz M. Eur J Med Res 2009, 14(5):223-227. read more...

Infektiosairaudet

Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440

Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801

Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.

Kardiologia

Training effect of eurythmy therapy on specific oscillations of heart rate variability. Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6

Eurythmy therapy increases specific oscillations of heart rate variability. Edelhäuser F, Antje Minnerop A, Trapp B, Büssing A 3 and Cysarz D. BMC Complementary and Alternative Medicine (2015) 15:167 DOI 10.1186/s12906-015-0684-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457978/

Anwendung von Cardiodoron® bei Patienten mit funktionellen Herz-Kreislauf-Beschwerden und/oder Schlafstörungen – Ergebnisse einer prospektiven, nichtinterventionellen Beobachtungsstudie. Claudia Rother,C. Forsch Komplementmed 2013;20:334–344 Published online: October 21, 2013 DOI: 10.1159/000355255

Keuhkosairaudet

Chemical pleurodesis using doxycycline and Viscum album extract.Song KS, Keum DY, Kim JB (2017) Korean Journal of Thoracic and Cardiovascular Surgery 50 (4), 281-286. DOI: 10.5090/kjtcs.2017.50.4.281

The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Park JB, Lee SA, Lee WS, Kim YH, Hwang JJ (2018) The management of chemical pleurodesis with Viscum album in patients with persistent air leakage. Journal of Thoracic Disease 10 (1), 371-376. Read more

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T,  Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019

Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801

Anthroposophic therapy for asthma: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Schnürer C, Glockmann A, Ziegler R, Willich SN, Kiene H.J Asthma Allergy 2009;2:111-28.

Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.

Korva-, nenä- ja kurkkutaudit

Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440

Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Hamre HJ, Glockmann A, Fischer M, Riley D, Baars E, Kiene H. . Drug Target Insights 2007;2:209-19.

Lastenneurologia

Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients. Harald J Hamre, Claudia M Witt, Gunver S Kienle, Christoph Meinecke, Anja Glockmann, Renatus Ziegler, Stefan N Willich, Helmut Kiene. International Journal of General Medicine 2010:3 239–253.

Lastentaudit

Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T,  Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019

Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801

Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more

Naistentaudit ja synnytykset

Spiritual needs of mothers with sick new born or premature infants– A cross sectional survey among German mothers. Büssing A, Waßermann U, Hvidt N Ch, Längler A, Thiel M; Australian College of Midwives 2017 DOI: https://doi.org/10.1016/j.wombi.2017.08.002

Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003

Effect of Bryophyllum pinnatum versus fenoterol on uterine contractility. Gwehenberger B, Rist L, Huch R, von Mandach U: Eur J Obstet Gynecol Reprod Biol 2004; 113(2):164-71.

Neurologia

Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003

Improvement of sleep quality during treatment with Bryophyllum. Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294

Anthroposophic Therapy for Migraine: A Two-Year Prospective Cohort Study in Routine Outpatient Settings. Harald J. Hamre, Claudia M. Witt, Gunver S. Kienle, Anja Glockmann, Renatus Ziegler, Andreas Rivoir, Stefan N. Willich and Helmut Kiene. The Open Neurology Journal, 2010; Volume 4:100-110. Open access

Onkologia ja mistelihoito

A 4-year non-randomized comparative phase–IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference. Hamre H J, Pham Van N, Kern Ch, Rau R, Klasen J, Schendel U, Gerlach L, Drabik A, Simon L; Patient Preference and Adherence 2018 12: 375-97 DOI: https://doi.org/10.2147/PPA.S145221

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronicke A, Li Oei S, Merkle A, Herbstreit C, Lemmens HP, Grah C, Kröz M, Matthes H, Schad F; Complementary Therapies in Medicine 2018 DOI: https://doi.org/10.1159/000478655

Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more

A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis. Schad F, Thronick e A, Steele ML, Merkle A, Matthes B, Grah C, et al. (2018). PLoS ONE 13(8): e0203058. Open access

Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access

Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access

Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text

Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access

Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. Thronicke A, Steele ML, Grah C, Matthes B, Schad F (2017). BMC Complementary and Alternative Medicine 17:534. 10 pp. DOI: 10.1186/s12906-017-2045-0

Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients. Schad F, Thronicke A, Merkle A, Matthes H, Steele ML (2017). Phytomedicine 36, 54-58. DOI: 10.2016/j.phymed.2017.09.004

Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model. Steinborn C, Klemd AM, Sanchez- Campillo A-S, Rieger S, Scheffen M, Sauer B, et al. (2017) PLoS ONE 12(7): e0181553. https://doi. org/10.1371/journal.pone.0181553

Safety of intravenously applied mistletoe extract – results from a phase I dose escalation study in patients with advanced cancer. Huber R, Schlodder D, Effertz C, Rieger S, Tröger W (2017). BMC Complementary and Alternative Medicine 17:465. 8 pp. DOI: 10.1185/s12906-017-1971-1

Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities. Schink M, Dehus O (2017). BMC Complemetary and Alternative Medicine 17:521. 8 pp. DOI: 10.1186/s12096-017-2028-1

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancerrelated fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design. Kröz M, Reif M, Glinz A, Berger B, Nikolaou A, Zerm R, Brinkhaus B, Girke M, Büssing A, Gutenbrunner C, and On behalf of the CRF-2 study group. BMC Cancer (2017) 17:166. DOI 10.1186/s12885-017-3142-7. Full article Open Access: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335840/

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors. Kienle GS, Mussler M, Dieter Fuchs and Kiene H. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 4628287, http://dx.doi.org/10.1155/2016/4628287

Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer. Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5

Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?
Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278. https://www.ncbi.nlm.nih.gov/pubmed/25602030

Mistletoe: From Basic Research to Clinical Outcomes in Cancer and Other Indications. Kröz M, Kienle GS, Feder G, Kaveri S and Rosenzweig S. Editorial. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 987527. http://dx.doi.org/10.1155/2014/987527

Use and Safety of Intratumoral Application of European Mistletoe (Viscum album L) Preparations in Oncology. Steele ML, Axtner J, Happe A, Kröz, M, Matthes, H and Schad F. Integr Cancer Ther March 2015 vol. 14 no. 2 140-148. DOI: 10.1177/1534735414563977 ict.sagepub.com.

Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Steele ML, Axtner J, Happe A, Kröz, Matthes and Schad F. Evidence-Based Complementary and Alternative Medicine, 2014; Article ID 236310. Volume 2014,http://dx.doi.org/10.1155/2014/236310

Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. Weissenstein U , Kunz M , Urech K and Baumgartner S. BMC Complementary and Alternative Medicine 2014, 14 :6 Open access: http://www.biomedcentral.com/1472-6882/14/6

Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Steele ML, Axtner J, Happe A, Kröz M, Matthes H and Schad F. Evidence-Based Complementary and Alternative Medicine Volume 2014, Article ID 724258, 11 pages http://dx.doi.org/10.1155/2014/724258

Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival. Tröger W, Galun M, Reif A et al. Eur J Cancer (2013) http://dx.doi.org/10.1016/j.ejca.2013.06.043

NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS et al. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 964592, http://dx.doi.org/10.1155/2013/964592

Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable Pancreas Carcinoma - A Retrospective Analysis. Schad F, Axtner J, Buchwald D, Happe A, Popp S, Kröz M and Matthes H. Integr Cancer Ther 2013 DOI: 10.1177/1534735413513637) http://ict.sagepub.com/content/early/2013/12/18/1534735413513637

Network Oncology (NO) – a Clinical Cancer Register for Health Services Research and the Evaluation of Integrative Therapeutic Interventions in Anthroposophic Medicine. Schad F, Axtner J, Happe A, Breitkreuz T, Paxino C, Gutsch J, Matthes B, Debus M, Kröz M, Spahn G, Riess H, von Laue H and Matthes H. Forsch Komplementmed 2013;20:353–360 Published online: October 24, 2013 DOI: 10.1159/000356204 Accessible online at: www.karger.com/fok

Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy. Seifert G, Rutkowski S, Jesse P, Madeleyn R, Reif M, Henze G and Längler A. J Pediatr Hematol Oncol 2011;33(3):105-10 read more...

Anthroposophic Medicine in Paediatric Oncology in Germany: Results of a Population-Based Retrospective Parental Survey. Alfred Längler, Claudia Spix, Friedrich Edelhäuser, David D. Martin, Genn Kameda, Peter Kaatsch and Georg Seifert. Pediatr Blood Cancer 2010 DOI 10.1002/pbc. read more...

Retrospective analysis of patients with advanced pancreatic cancer under palliative treatment and additive intratumoral application of viscum album l. F. Schad, D. Buchwald, A. Merkle, S. Popp, M. Kroez, H. Matthes: J Clin Oncol 29: 2011 (suppl; abstract e14538). online:http://abstract.asco.org/AbstView_102_82630.

Influence of Viscum album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies.Kienle GS and Kiene H. Integrative Cancer Therapies 2010:1-16.

Molecular mistletoe therapy: friend or foe in established anti-tumor protocols? A multicenter, controlled, retrospective pharmaco-epidemiological study in pancreas cancer. Matthes H, Friedel WE, Bock PR, Zanker KS. Curr Mol Med 2010; 10: 430-9.read more...

Durable tumour responses following primary high dose induction with mistletoe extracts: Two case reports. Orange M, Fonseca M, Lace A, vonLaue HB, Geider S. European Journal of Integrative Medicine 2010;2:63-69.read more...

The influence of self- and autonomic regulation on cancer-related fatigue and distress in breast and colorectal cancer patients - A prospective study.Kröz M, Zerm R, Kuhnert N, Brauer D, Laue HBv, Bockelbrink A, Reif M, Schad F, Feder G, Heckmann C, Laue von S, Willich S, Girke M. European Journal of Integrative Medicine 2009;1(4):182. read more...

Prospective controlled cohort studies on long-therapy of cervical cancer patients with a mistletoe preparation (Iscador). Grossarth-Maticek R, Ziegler R.. Forsch Komplementärmed 2007;14:140-7.

A five-year follow-up of quality of life in women with breast cancer in anthroposophic and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. eCam 2006.

Coping in women with breast cancer in complementary and conventional care over 5 years measured by the mental adjustment to cancer scale.Carlsson M, Arman M, Backman M, Hamrin E. J Altern Complement Med 2005;11(3):441-447

Evaluation of quality of life/life satisfaction in women with breast cancer in complementary and conventional care. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. Acta Oncol. 2004;43(1):27-34.

Mistelihoito: Tuoremmat tutkimustulokset

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access

A 4-year non-randomized comparative phase–IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference. Hamre H J, Pham Van N, Kern Ch, Rau R, Klasen J, Schendel U, Gerlach L, Drabik A, Simon L; Patient Preference and Adherence 2018 12: 375-97 DOI: https://doi.org/10.2147/PPA.S145221

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronicke A, Li Oei S, Merkle A, Herbstreit C, Lemmens HP, Grah C, Kröz M, Matthes H, Schad F; Complementary Therapies in Medicine 2018 DOI: https://doi.org/10.1159/000478655

Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more

A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis. Schad F, Thronick e A, Steele ML, Merkle A, Matthes B, Grah C, et al. (2018). PLoS ONE 13(8): e0203058. Open access

Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Thronicke A, Li Oei S, Merkle A, Matthes H, Schad, F (2018) Medicines 2018, 5, 100; doi:10.3390/medicines5030100. Open access

Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access

Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text

Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text

Integrative cancer care in a certified Cancer Centre of a German Anthroposophic hospital. Thronickea A, Li Oeia S, Merklea A Herbstreit C, Lemmens H-P, Grah C, Kröz M, Matthes H, Schad F. Complementary Therapies in Medicine, Volume 40, October 2018, Pages 145-150 https://doi.org/10.1016/j.ctim.2018.03.012 Open access

Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. Thronicke A, Steele ML, Grah C, Matthes B, Schad F (2017). BMC Complementary and Alternative Medicine 17:534. 10 pp. DOI: 10.1186/s12906-017-2045-0

Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients. Schad F, Thronicke A, Merkle A, Matthes H, Steele ML (2017). Phytomedicine 36, 54-58. DOI: 10.2016/j.phymed.2017.09.004

Safety of intravenously applied mistletoe extract – results from a phase I dose escalation study in patients with advanced cancer. Huber R, Schlodder D, Effertz C, Rieger S, Tröger W (2017). BMC Complementary and Alternative Medicine 17:465. 8 pp. DOI: 10.1185/s12906-017-1971-1

Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities. Schink M, Dehus O (2017). BMC Complemetary and Alternative Medicine 17:521. 8 pp. DOI: 10.1186/s12096-017-2028-1

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancerrelated fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design. Kröz M, Reif M, Glinz A, Berger B, Nikolaou A, Zerm R, Brinkhaus B, Girke M, Büssing A, Gutenbrunner C, and On behalf of the CRF-2 study group. BMC Cancer (2017) 17:166. DOI 10.1186/s12885-017-3142-7. Full article Open Access: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335840/

Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model. Steinborn C, Klemd AM, Sanchez- Campillo A-S, Rieger S, Scheffen M, Sauer B, et al. (2017) PLoS ONE 12(7): e0181553. https://doi. org/10.1371/journal.pone.0181553

Mistelihoito: katsaukset

Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline. Gary H. Lyman, Heather Greenlee, Kari Bohlke, Ting Bao, Angela M. DeMichele, Gary E. Deng, Judith M. Fouladbakhsh, Brigitte Gil, Dawn L. Hershman, Sami Mansfield, Dawn M. Mussallem, Karen M. Mustian, Erin Price, Susan Rafte, and Lorenzo Cohen. J Clin Oncol 36:2647-2655. © 2018 by American Society of Clinical Oncology. Open access (pdf)

Safety of higher dosages of Viscum album L. in animals and humans - systematic review of immune changes and safety parameters. Kienle GS, Grugel R, Kiene H: BMC Complement Altern Med 2011, 11:72 http://www.biomedcentral.com/content/pdf/1472-6882-11-72.pdf

Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research. Kienle GS, Glockmann A, Schink M, Kiene H: Journal of Experimental & Clinical Cancer Research: CR 2009, 28:79 http://www.biomedcentral.com/content/pdf/1756-9966-28-79.pdf

Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extracts. Kienle GS, Kiene H: Eur J Med Res 2007, 12:103-119 http://www.daig-net.de/site-content/die-daig/fachorgan/2007-1/ejomr-2007_3-pdfs/S.103_Kienle.pdf

Influence of Viscum Album L (European Mistletoe) Extracts on Quality of Life in Cancer Patients: A Systematic Review of Controlled Clinical Studies. Kienle GS, Kiene H: Integr Cancer Ther 2010, 9:142-157 http://ict.sagepub.com/content/9/2/142.long

Mistletoe therapy in oncology (Review). Horneber MA, Bueschel G, Huber R, Linde K, Rostock M. Reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2008, Issue 2. http://www.thecochranelibrary.com

Mistelihoito: Satunnaistetut kontrolloidut tutkimukset

Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2014. Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Dtsch Ärztebl Int 111(29–30): 493–502. doi:10.3238/arztebl.2014.0493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150026/; http://www.aerzteblatt.de/pdf.asp?id=161151

 

Additional therapy with a mistletoe product during adjuvant chemotherapy of breast cancer patients improves quality of life. Tröger, W.; Ždrale, Z.; Tišma, N.; Matijašević, M. 2014. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evid Based Complement Alternat Med 2014: 430518. doi:10.1155/2014/430518. https://www.hindawi.com/journals/ecam/2014/430518/

 

Viscum [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival. Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2013. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomized clinical trial on overall survival. Eur. J. Cancer 49(18): 3788–3797. https://www.ncbi.nlm.nih.gov/pubmed/23890767; http://www.ejcancer.com/article/S0959-8049%2813%2900550-9/pdf

 

NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Mansky PJ, Wallerstedt DB, Sannes TS, Stagl J, Johnson LL, Blackman MR, Grem JL, Swain SM, Monahan BP: Evidence-Based Complementary and Alternative Medicine 2013, 2013: 964592 http://www.hindawi.com/journals/ecam/2013/964592/

 

Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with a mistletoe extract to chemotherapy alone. Tröger, W.; Ždrale, Z.; Stanković, N.; Matijašević, M. 2012. Fiveyear follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl) 6: 173–180. doi:10.4137/BCBCR.S10558. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493140/

 

Quality of life is improved in breast cancer patients by Standardised Mistletoe Extract PS76A2 during chemotherapy and follow-up: a randomised, placebo-controlled, double-blind, multicentre clinical trial. Semiglasov VF, Stepula VV, Dudov A, Schnitker J, Mengs U: Anticancer Res 2006, 26:1519-1530 http://ar.iiarjournals.org/content/26/2B/1519.full.pdf

 

Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Piao BK, Wang YX, Xie GR, Mansmann U, Matthes H, Beuth J, Lin HS: Anticancer Res 2004, 24:303-309 http://ar.iiarjournals.org/content/24/1/303.full.pdf

Mistelihoito: Ei-satunnaistetut, kontrolloidut tutkimukset ja kohorttitutkimukset

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors. Kienle GS, Mussler M, Dieter Fuchs and Kiene H. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 4628287,

http://dx.doi.org/10.1155/2016/4628287

 

Targeting inflammation in cancer-related-fatigue: a rationale for mistletoe therapy as supportive care in colorectal cancer patients. Bock, P.R.; Hanisch, J.; Matthes, H.; Zänker, K.S. 2014. Targeting inflammation in cancer-related-fatigue: a rationale for mistletoe therapy as supportive care in colorectal cancer patients. Inflamm Allergy Drug Targets 13(2): 105–111. https://www.ncbi.nlm.nih.gov/pubmed/24766319 

 

Intratumoral mistletoe therapy in patients with unresectable pancreas carcinoma: a retrospective analysis.

Schad, F.; Axtner, J.; Buchwald, D.; Happe, A.; Popp, S.; Kröz, M.; Matthes, H. 2013. Intratumoral Mistletoe (Viscum album L) Therapy in Patients with Unresectable Pancreas Carcinoma: A Retrospective Analysis. Integr Cancer Ther 13(4): 332–340. https://www.ncbi.nlm.nih.gov/pubmed/24363283

 

Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Eisenbraun, J.; Scheer, R.; Kröz, M.; Schad, F.; Huber, R. 2011. Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine 18(2–3): 151–157. doi:10.1016/j.phymed.2010.06.013. https://www.ncbi.nlm.nih.gov/pubmed/20724129

 

Anthroposophic supportive treatment in children with medullo-blastoma receiving first-line therapy.

 Seifert, G.; Rutkowski, S.; Jesse, P.; Madeleyn, R.; Reif, M.; Henze, G.; Längler, A. 2011. Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy. J. Pediatr. Hematol. Oncol. 33(3): e105–108. doi:10.1097/ MPH.0b013e31820946d3. https://www.ncbi.nlm.nih.gov/pubmed/21368673

Mistelihoito: havaintotutkimukset, tapausselostukset ja tapaussarjatutkimukset

Durable Clinical Remission of a Skull Metastasis Under Intralesional Viscum album Extract Therapy - A Case Report. Werthmann PG, Huber R, Kienle GS. Head & Neck 2018;00:1–5. Read more

A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Werthmann PG, Kindermann L, Kienle GS. Complementary Therapies in Medicine. Volume 38, June 2018, Pages 58-60. Read more

Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Anticancer Research. September 2018 vol. 38 no. 9 5363-5369. doi: 10.21873/anticanres.12865 Open access

Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M u. a. . Medicine. Dezember 2018;97(49):e13243. Full text

Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ. A CARE compliant case report.Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Medicine: November 2018 - Volume 97 - Issue 48 - p e13420, doi: 10.1097/MD.0000000000013420. Full text

Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. Werthmann, P.G.; Helling, D.; Heusser, P.; Kienle, G.S. 2014. Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. BMJ Case Rep 2014; pii:bcr2013203180. doi:10.1136/bcr-2013-203180. http://casereports.bmj.com/content/2014/bcr-2013-203180.abstract

Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts. Werthmann, P.G.; Sträter, G.; Friesland, H.; Kienle, G.S. 2013. Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts – a case report. Phytomedicine 20(3–4): 324–327. doi:10.1016/j.phymed.2012.11.001. https://www.ncbi.nlm.nih.gov/pubmed/23394841

Mistelihoito: yhteenveto tilanne 3/2017

Lisää tutkimustietoa mistelihoidosta (Tilanne 3/2017)

Ortopedia ja traumatologia

Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings. Hamre HJ, Kiene H, Glockmann A, Ziegler R, Kienle GS. BMC Res Notes 2013;6(269):doi:10.1186/1756-0500-6-269.

Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS) Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res. 2004 Jul 30;9(7):351-60. read more.

Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more

Predictors of outcome after 6 and 12 months following anthroposophic therapy for adult outpatients with chronic disease: a secondary analysis from a prospective observational study. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Willich SN, Kiene H. BMC Research Notes 2010 Aug 3;3(218). read more

Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Journal of Pain Research 2009;2:75-85. read more

Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Kienle GS, Willich SN, et al. Drug Design, Development and Therapy 2008;2:25-37.

Anthroposophic vs. conventional therapy for chronic low back pain: a prospective comparative study. Hamre H, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res 2007;12:302-10.

Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Complement Altern Med 2007;7(10):DOI 10.1186/1472-6882-7-10.

Psykiatria

Course of life satisfaction in patients with depressive and addictive disorders after therapeutic intervention. Büssing A, Heusser P, Mundle G: International Journal of Social Psychiatry 2011; first published on March 25, 2011 as doi:10.1177/0020764010390498

Anthroposophic therapy for anxiety disorders: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Clinical Medicine: Psychiatry 2009;2:17-31 read more...

Sisätaudit

Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism.
Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/

Terveydenhuolto

Do NHS GP surgeries employing GPs additionally trained in integrative or complementary medicine have lower
antibiotic prescribing rates? Retrospective cross-sectional analysis of national primary care prescribing data in England in 2016. van der Werf ET, Duncan LJ, Flotow P, et al. BMJ Open 2018;8:e020488. doi:10.1136/ bmjopen-2017-020488. Open access

Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study. Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8

Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer. Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5

Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study. Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8

 

Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Rossi, E.; Vita, A.; Baccetti, S.; Di Stefano, M.; Voller, F.; Zanobini, A. 2015. Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Support Care Cancer 23(6): 1795–1806. doi:10.1007/s00520-014-2517-4. https://www.ncbi.nlm.nih.gov/pubmed/25471177

 

The use and safety of intravenous application of mistletoe preparations in oncology.

Steele, M.L.; Axtner, J.; Happe, A.; Kröz, M.; Matthes, H.; Schad, F. 2015. Use and safety of intratumoral application of European mistletoe (Viscum album L) preparations in Oncology. Integr Cancer Ther 2015; 14(2): 140–148. doi:10.1177/1534735414563977. https://www.hindawi.com/journals/ecam/2014/236310/

 

Influence of anthroposophic lifestyle on the concentration of metals in placenta and cord blood. Fagerstedt, S.; Kippler, M.; Scheynius, A.; Gutzeit, C.; Mie, A.; Alm, J.; Vahter, M. 2015. Anthroposophic lifestyle influences the concentration of metals in placenta and cord blood. Environ. Res. 136: 88–96. doi:10.1016/j.envres.2014.08.044. https://www.ncbi.nlm.nih.gov/pubmed/25460625

 

Adverse drug reactions and expected effects to therapy with subcutaneous mistletoe extracts in cancer patients. Steele, M.L.; Axtner, J.; Happe, A.; Kröz, M.; Matthes, H.; Schad, F. 2014. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Evid Based Complement Alternat Med 2014: 724258. doi:10.1155/2014/724258. https://www.hindawi.com/journals/ecam/2014/724258/

 

Human breast milk in relation to allergic sensitization and anthroposophic lifestyle. Torregrosa Paredes, P.; Gutzeit, C.; Johansson, S.; Admyre, C.; Stenius, F.; Alm, J.; Scheynius, A.; Gabrielsson, S. 2014. Differences in exosome populations in human breast milk in relation to allergic sensitization and lifestyle. Allergy 69(4): 463–471. doi:10.1111/all.12357. https://www.ncbi.nlm.nih.gov/pubmed/24428462

 

Influence of alternative lifestyles on self-reported body weight and health characteristics in women. Simoes-Wüst, A.P.; Kummeling, I.; Mommers, M.; Huber, M.A.; Rist, L.; van de Vijver, L.P.; Dagnelie, P.C.; Thijs, C. 2014. Influence of alternative lifestyles on self-reported body weight and health characteristics in women. Eur J Public Health 24(2): 321–327. doi:10.1093/eurpub/ckt045. https://www.ncbi.nlm.nih.gov/pubmed/23639916

 

Parental attitudes and decision-making regarding MMR vaccination in an anthroposophic community. Byström, E.; Lindstrand, A.; Likhite, N.; Butler, R.; Emmelin, M. 2014. Parental attitudes and decision-making regarding MMR vaccination in an anthroposophic community in Sweden – a qualitative study. Vaccine 32(50): 6752–6757. doi:10.1016/j.vaccine.2014.10.011. https://www.ncbi.nlm.nih.gov/pubmed/25454859 

 

The consumer quality index anthroposophic healthcare: a construction and validation study. Koster, E.B.; Ong, R.R.; Heybroek, R.; Delnoij, D.M.; Baars, E.W. 2014. The consumer quality index anthroposophic healthcare: a construction and validation study. BMC Health Serv Res 2014; 14: 148. doi:10.1186/1472-6963-14-148. https://www.ncbi.nlm.nih.gov/pubmed/24694288

 

6-year comparative economic evaluation of healthcare costs and mortality rates of Dutch patients from conventional and CAM GPs. Baars, E.W.; Kooreman, P. 2014. A 6-year comparative economic evaluation of healthcare costs and mortality rates of Dutch patients from conventional and CAM GPs. BMJ Open 2014; 4(8): e005332. doi:10.1136/bmjopen-2014-005332. Erratum in:BMJ Open 2014; 4(9): e005332corr1. http://bmjopen.bmj.com/content/4/8/e005332.full

 

Integration of anthroposophic medicine in supportive breast cancer care. Ben-Arye, E.; Schiff, E.; Levy, M.; Raz, O.G.; Barak, Y.; Bar-Sela, G. 2013. Barriers and challenges in integration of Anthroposophic medicine in supportive breast cancer care. Springerplus 2013; 2: 364. doi:10.1186/2193-1801-2-364. https://www.ncbi.nlm.nih.gov/pubmed/23961426

 

Complementary and alternative medicine in paediatrics in daily practice in Europe. Längler, A.; Zuzak, T.J. 2013. Complementary and alternative medicine in paediatrics in daily practice – a European perspective. Complement Ther Med 2013; 21 (Suppl 1): 26–33. doi:10.1016/j.ctim.2012.01.005. http://search.proquest.com/openview/b1009f87b65265381d3821a0de5dab90/1.pdf?pq-origsite=gscholar

https://www.ncbi.nlm.nih.gov/pubmed/23578914 

 

Use of complementary and alternative medicine in healthy children and children with chronic medical conditions in Germany. Gottschling, S.; Gronwald, B.; Schmitt, S.; Schmitt, C.; Längler, A.; Leidig, E.; Meyer, S.; Baan, A.; Shamdeen, M.G.; Berrang, J.; Graf, N. 2013. Use of complementary and alternative medicine in healthy children and children with chronic medical conditions in Germany. Complement Ther Med 2013; (Suppl. 1): 61–69.doi:10.1016/j.ctim.2011.06.001. https://www.ncbi.nlm.nih.gov/pubmed/23578919

 

Network Oncology (NO) – a clinical cancer register for health services research and the evaluation of integrative therapeutic interventions in anthroposophic medicine. Schad, F.; Axtner, J.; Happe, A.; Breitkreuz, T.; Paxino, C.; Gutsch, J.; Matthes, B.; Debus, M.; Kröz, M.; Spahn, G.; Riess, H.; von Laue, H.B.; Matthes, H. 2013. Network Oncology (NO) – a clinical cancer register for health services research and the evaluation of integrative therapeutic interventions in Anthroposophic medicine. Forsch Komplementärmed 20(5): 353–360. doi:10.1159/000356204. http://www.karger.com/Article/Abstract/356204

 

Cost analysis of anthroposophical inpatient treatment based on DRG data. Heinz, J.; Fiori, W.; Heusser, P.; Ostermann, T. 2013. Cost Analysis of Integrative Inpatient Treatment Based on DRG Data: The Example of Anthroposophic Medicine. Evid Based Complement Alternat Med 2013: 748932. doi:10.1155/2013/748932. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572651/

 

Patients whose GP knows anthroposophic and other complementary medicine tend to have lower costs and live .

Kooreman, P.; Baars, E.W. 2012. Patients whose GP knows complementary medicine tend to have lower costs and live longer. Eur J Health Econ 13(6): 769–776. doi:10.1007/s10198-011-0330-2. https://www.ncbi.nlm.nih.gov/pubmed/21695547

 

Prescribing pattern of Bryophyllum preparations among a network of anthroposophic physicians. Simoes-Wüst, A.P.; Jeschke, E.; Mennet, M.; Schnelle, M.; Matthes, H.; von Mandach, U. 2012. Prescribing pattern of Bryophyllum preparations among a network of Anthroposophic physicians. Forsch Komplementärmed 19(6): 293–301. doi:10.1159/000345841. https://www.karger.com/Article/Pdf/345841

 

Depression, comorbidities, and prescriptions of antidepressants in a German network of GPs and specialists with subspecialisation in anthroposophic medicine: a longitudinal observational study. Jeschke, E.; Ostermann, T.; Vollmar, H.C.; Tabali, M.; Matthes, H. 2012. Depression, Comorbidities, and Prescriptions of Antidepressants in a German Network of GPs and Specialists with Subspecialisation in Anthroposophic Medicine: A Longitudinal Observational Study. Evid Based Complement Alternat Med 2012: 508623. doi:10.1155/2012/508623. https://www.ncbi.nlm.nih.gov/pubmed/23304204

 

Adverse drug reactions to anthroposophic and homeopathic solutions for injection: a systematic evaluation of German pharmacovigilance databases. Jong, M.C.; Jong, M.U.; Baars, E.W. 2012. Adverse drug reactions to anthroposophic and homeopathic solutions for injection: a systematic evaluation of German pharmacovigilance databases. Pharmacoepidemiol Drug Saf 21(12): 1295–1301.:10.1002/pds.3298. https://www.ncbi.nlm.nih.gov/pubmed/22692862

 

Adverse drug reactions for anthroposophical and conventional drugs detected in the network of anthroposophical physicians. Tabali, M.; Ostermann, T.; Jeschke, E.; Witt, C.M.; Matthes, H. 2012. Adverse drug reactions for CAM and conventional drugs detected in a network of physicians certified to prescribe CAM drugs. J Manag Care Pharm 18(6): 427–438. https://www.hindawi.com/journals/ecam/2014/724258/

 

Adverse drug reactions in a complementary medicine hospital: a prospective, intensified surveillance study. Süsskind, M.; Thürmann, P.A.; Lüke, C.; Jeschke, E.; Tabali, M.; Matthes, H.; Ostermann, T. 2012. Adverse drug reactions in a complementary medicine hospital: a prospective, intensified surveillance study. Evid Based Complement Alternat Med 2012: 320760. doi:10.1155/2012/320760. https://www.ncbi.nlm.nih.gov/pubmed/22315630

 

Usage of alternative medical systems and anthroposophic medicine by older German adults. Büssing, A.; Ostermann, T.; Heusser, P.; Matthiessen, P.F. 2011. Usage of alternative medical systems, acupuncture, homeopathy and anthroposophic medicine, by older German adults. Zhong Xi Yi Jie He Xue Bao 2011; 9(8): 847–856. https://www.ncbi.nlm.nih.gov/pubmed/21849145 

 

Anthroposophic medicine in pediatric primary care. Jeschke, E.; Ostermann, T.; Tabali, M.; Kröz, M.; Bockelbrink, A.; Witt, C.M.; Willich, S.N.; Matthes, H. 2011. Anthroposophic medicine in pediatric primary care: a prospective, multi-center observational study on prescribing patterns. Altern Ther Health Med 17(2): 18–28. https://www.ncbi.nlm.nih.gov/pubmed/21717821

Yleislääketiede

Do NHS GP surgeries employing GPs additionally trained in integrative or complementary medicine have lower
antibiotic prescribing rates? Retrospective cross-sectional analysis of national primary care prescribing data in England in 2016. van der Werf ET, Duncan LJ, Flotow P, et al. BMJ Open 2018;8:e020488. doi:10.1136/ bmjopen-2017-020488. Open access

Patient-centered outcomes on quality of life and Anthroposophic healthcare: a qualitative triangulation study. Koster EB, Baars EW and Delnoij DMJ. Qual Life Res. 2016. DOI 10.1007/s11136-016-1276-8 http://link.springer.com/article/10.1007/s11136-016-1276-8

Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals.Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/

Patients whose GP knows complementary medicine tend to have lower costs and live longer. Peter Kooreman P and Baars EW (2010): Eur J Health Econ DOI 10.1007/s10198-011-0330-2

Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: An observational study. Lambrigger-Steiner C, Simões-Wüst AP, Kuck A, Fürer K, Hamburgere M and von Mandach U. Phytomedicine 2014; 21: 753–757. http://dx.doi.org/10.1016/j.phymed.2013.11.003

Improvement of sleep quality during treatment with Bryophyllum. Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294

Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS) Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res. 2004 Jul 30;9(7):351-60. read more.

Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. Hamre HJ, Witt CM, Kienle GS, Meinecke C, Glockmann A, Willich SN, Kiene H. BMC Pediatr 2009;9:39 read more

Predictors of outcome after 6 and 12 months following anthroposophic therapy for adult outpatients with chronic disease: a secondary analysis from a prospective observational study. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Willich SN, Kiene H. BMC Research Notes 2010 Aug 3;3(218). read more

Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. Hamre HJ, Witt CM, Kienle GS, Glockmann A, Ziegler R, Willich SN, Kiene H. Journal of Pain Research 2009;2:75-85. read more

Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Kienle GS, Willich SN, et al. Drug Design, Development and Therapy 2008;2:25-37.

Anthroposophic vs. conventional therapy for chronic low back pain: a prospective comparative study. Hamre H, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eur J Med Res 2007;12:302-10.

Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Complement Altern Med 2007;7(10):DOI 10.1186/1472-6882-7-10.

Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients. Harald J Hamre, Claudia M Witt, Gunver S Kienle, Christoph Meinecke, Anja Glockmann, Renatus Ziegler, Stefan N Willich, Helmut Kiene. International Journal of General Medicine 2010:3 239–253.

Lääketieteen koulutuksen ja laadunvalvonnan tutkimus

Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/

 

Spirituality in medical doctors and their relation to specific views of illness and dealing with their patients’ individual situation. Büssing, A.; Hirdes, A.T.; Baumann, K.; Hvidt, N.C.; Heusser, P. 2013. Aspects of spirituality in medical doctors and their relation to specific views of illness and dealing with their patients’ individual situation. Evid Based Complement Alternat Med 2013: 734392. doi:10.1155/2013/734392. https://www.hindawi.com/journals/ecam/2013/734392/

 

Problems and problem solving in integrative postgraduate medical training at anthroposophic hospitals.

Heusser, P.; Eberhard, S.; Weinzirl, J.; Orlow, P.; Berger, B. 2014. Problems in integrative postgraduate medical training of physicians at anthroposophic hospitals in Germany and Switzerland. Forsc Komplementärmed 21(4): 223–230. doi:10.1159/000366187. https://www.ncbi.nlm.nih.gov/pubmed/25427519

 

Quality of postgraduate medical training in anthroposophic hospitals in Germany and Switzerland.

Heusser, P.; Eberhard, S.; Berger, B.; Weinzirl, J.; Orlow, P. 2014. The subjectively perceived quality of postgraduate medical training in integrative medicine within the public healthcare systems of Germany and Switzerland: the example of Anthroposophic hospitals. BMC Complement Altern Med 2014; 14: 191. doi:10.1186/1472-6882-14-191. https://www.ncbi.nlm.nih.gov/pubmed/24934998

 

Active student participation may enhance patient centeredness: patients’ assessments of the clinical education ward for integrative and anthroposophical medicine.

Scheffer, C.; Tauschel, D.; Neumann, M.; Lutz, G.; Valk-Draad, M.; Edelhäuser, F. 2013. Active student participation may enhance patient centeredness: patients’ assessments of the clinical education ward for integrative medicine. Evid Based Complement Alternat Med 2013: 743832. doi:10.1155/2013/743832. https://www.hindawi.com/journals/ecam/2013/743832/

 

Integrative medical education: educational strategies and preliminary evaluation of the Integrated Curriculum for Anthroposophic Medicine. Scheffer, C.; Tauschel, D.; Neumann, M.;, G.; Cysarz, D.; Heusser, P.; Edelhäuser, F. 2012. Integrative medical education: educational strategies and preliminary evaluation of the Integrated Curriculum for Anthroposophic Medicine (ICURAM). Patient Educ Couns 89(3): 447–454. doi:10.1016/j.pec.2012.04.006. https://www.ncbi.nlm.nih.gov/pubmed/22738823

 

Towards non-reductionistic medical anthropology, medical education and practitioner-patient-interaction: the example of Anthroposophic Medicine. Heusser, P.; Scheffer, C.; Neumann, M.; Tauschel, D.; Edelhäuser, F. 2012. Towards non-reductionistic medical anthropology, medical education and practitioner patient-interaction: the example of Anthroposophic Medicine. Patient Educ Couns 89(3): 455–460. doi:10.1016/j.pec.2012.01.004. https://www.ncbi.nlm.nih.gov/pubmed/22306457

Antroposofinen lääketiede on integratiivinen lääketiede

Inverse relationship between reduced fatigue and severity of anemia in oncology patients treated with integrative medicine: understanding the paradox. Ben-Arye E, Dahan O, Shalom-Sharabi I, Samuels N (2018) Supportive Care in Cancer. 10 pp. DOI: 10.1007/s00520-018-4271-5

Anthroposophy and Integrative Care at the End of Life. Ciro Augusto Floriani CA. Alternative and complementary therapies. 2016; 22(3): DOI: 10.1089/act.2016.29055.caf http://online.liebertpub.com/doi/abs/10.1089/act.2016.29055.caf

Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Rossi, E.; Vita, A.; Baccetti, S.; Di Stefano, M.; Voller, F.; Zanobini, A. 2015. Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe. Support Care Cancer 23(6): 1795–1806. doi:10.1007/s00520-014-2517-4. https://www.ncbi.nlm.nih.gov/pubmed/25471177

Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals.Büssing A, Lötzke D, Glöckler M, Heusser P. 2015. Influence of spirituality on cool down reactions, work engagement, and life satisfaction in anthroposophic health care professionals. Evid Based Complement Alternat Med. doi: 10.1155/2015/754814. https://www.hindawi.com/journals/ecam/2015/754814/

Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue?
Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278. https://www.ncbi.nlm.nih.gov/pubmed/25602030

Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Hamre HJ, Glockmann A, Schwarz R, Riley DS, Baars EW, Kiene H and Kienle GS. Evidence-Based Complementary and Alternative Medicine Volume 2014 (2014), Article ID 243801, 17 pages Full article open access: http://dx.doi.org/10.1155/2014/243801

Patients whose GP knows complementary medicine tend to have lower costs and live longer. Peter Kooreman P and Baars EW (2010): Eur J Health Econ DOI 10.1007/s10198-011-0330-2

Anthroposophic Medicine: An Integrative Medical System Originating in Europe. Kienle GS, Albonico H-U, Baars, Hamre HJ, Zimmermann P and Kiene H. Global Adv Health Med. 2013;2(6):20-31. DOI: 10.7453/gahmj.2012.087

Overview of the Publications From the Anthroposophic Medicine Outcomes Study (AMOS): A Whole System Evaluation Study. Hamre HJ, Kiene H, Ziegler R, Tröger W, Meinecke C, Schnürer C, Vögler H, Glockmann A, Kienle S: Global Adv Health Med. 2014;3(1):54-70. DOI: 10.7453/gahmj.2013.010.
Full article: http://www.gahmj.com/doi/pdf/10.7453/gahmj.2013.010

Opposite Drug Prescription and Cost Trajectories following Integrative and Conventional Care for Pain – A Case-Control Study. Sundberg, Petzold M, Kohls N and Falkenberg T. PLoS ONE 2014; 9(5): e96717. doi:10.1371/journal.pone.0096717.

Complementary Therapy Systems and Their Integrative Evaluation. Kienle GS, Albonico H-U, Fischer L, Frei-Erb M, Hamre HJ, Heusser P, Matthiessen PF, Renfer A, Kiene H. Journal of Science and Healing 2011(7/3): 175-187. read more (free download)

Clinical judgement and the medical profession. Gunver S Kienle and Helmut Kiene. Journal of Evaluation in Clinical Practice 2010: doi:10.1111/j.1365-2753.2010.01560.x read more

Mindfulness-Based Stress Reduction (MBSR) for integrative Cancer Care – A summary of evidence. Musial F, Büssing A, Heusser P, Kyung-Eun C, Ostermann T: Forschende Komplementärmedizin 2011; 18: (Online August 8, 2011; DOI: 10.1159/000330714)

The challenges of complexity. Wolf U, Winkler M, Ephraim M, Hamre HJ, Lemann D: Primary Care 2011; 11(10):174-175.

Professional treatment in the context of medical pluralism - A German perspective. Kiene H, Brinkhaus B, Fischer G, Girke M, Hahn EG, Hoppe HD, Jütte R, Kraft K, Klitzsch W, Matthiessen PF, Meister P, Michalsen A, Teut M, Willich SN, Heimpel H. Europaen Journal of Integrative Medicine 2010;2:53-56 read more

A pilot study on the effects of a team building process on the perception of work environment in an integrative hospital for neurological rehabilitation. Ostermann T, Bertram M, Büssing A BMC Complementary and Alternative Medicine 2010; 10, 10 (http://www.biomedcentral.com/1472-6882/10/10: 25-44) (pp. 1-10) read more

An integrative approach of cancer treatment with mistletoe therapy, surgery, irradiation and chemotherapy in CAM settings. Schad F, Merkle A, Hoffmann G, Lenneweit G, Spahn G, Hesse M, Paxino C, Wellmann G, Matthes B, Baute R, Breitkreuz T, Matthes H. European Journal of Integrative Medicine 2009;1(4):184. read more

Integrative medical education: Educational strategies and preliminary evaluation of the Integrated Curriculum for Anthroposophic Medicine (ICURAM). Scheffer C, et al. Patient Educ Couns (2012), read more

Medicinal Systems of Complementary and Alternative Medicine: A Cross-Sectional Survey at a Pediatric Emergency Department. Zuzak J, Zuzak-Siegrist I, Rist L, Staubli G, Simoñes-Wüst AP. The Journal of Alternative and Complementary Medicine, Volume 16, Number 4, 2010, pp. 473-479.

Anthroposophic perspectives in primary care. Cantor IS, Rosenzweig S, Volume 24, Number 4, December 1997.

Eurytmia terapia (hoitoeurytmia)

Training effect of eurythmy therapy on specific oscillations of heart rate variability.
Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6

A systematic literature review on the effectiveness of eurythmy therpy.
Lötzke D, Heusser P, Büssing A. J Integr Med. 2015 Jul;13(4):217-30. doi: 10.1016/S2095-4964(15)60163-7. http://www.ncbi.nlm.nih.gov/pubmed/25808905

Eurythmy therapy increases specific oscillations of heart rate variability. Edelhäuser F, Antje Minnerop A, Trapp B, Büssing A 3 and Cysarz D. BMC Complementary and Alternative Medicine (2015) 15:167 DOI 10.1186/s12906-015-0684-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457978/

Eurythmy Therapy in Anxiety. Schwab J, Murphy J, Andersson P, Lunde G, Kiene H, Hamre HJ, Kienle GS: Alternative Therapies in Health and Medicine 2011;17(4): 58-65. Read more

Inner Correspondence and Peacefulness with Practices among Participants in Eurythmy Therapy and Yoga: A Validation Study. Büsssing A, Edelhäuser F, Weisskircher A, Fouladbakhsh JM and Heusser P. Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 329023, 9 pages doi:10.1155/2011/329023 read more

Therapeutic Eurythmy-movement therapy for children with attention deficit hyperactivity disorder (ADHD): a pilot study. Majorek M, Tuchelmann T, Heusser P. Complement Ther Nurs Midwifery 2004 10(1):46-53.

Effects of complementary eurythmy therapy on heart rate variability. Seifert et al:, Complement Ther Med (2008), doi:10.1016/j.ctim.2008.09.005)

Eurythmy therapy in chronic disease: a four-year propective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. BMC Public Health 2007;7(61):DOI 10.1186/1471-2458-7-61.

Ulkoiset hoidot, sairaanhoito, hieronnat

Clinical Outcomes of Rhythmical Massage. A Prospective Cohort Study with Swiss Outpatients. Wälchli C, Saltzwedel G, Rist L, Bach-Meguid B, Eberhard J, Decker M and Simões-Wüst AP. Alternative and Complementary Therapies. October 2014, 20(5): 248-258. doi:10.1089/act.2014.20509. http://online.liebertpub.com/doi/abs/10.1089/act.2014.20509

Rhythmical massage therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. J Altern Complement Med 2007;13(6):635-42.

Therkleson T, Sherwood P: Patient’s experience of the external therapeutic application of ginger by anthroposophically trained nurses. Indio-Pacific Journal of Phenomenology 2005;4:1-11.

Antroposofiset taideterapiat

Effects of live music therapy on heart rate variability and selfreported stress and anxiety among hospitalized pregnant women: A randomized controlled trial. Teckenberg-Jansson P, Turunen S, Pölkki T, Lauri-Haikala M-J, Lipsanen J, Henelius A, Aitokallio-Tallberg A, Pakarinen S, Leinikka M and Huotilainen M. Nordic Journal of Music Therapy 2019, 28:1, 7-26. DOI: 10.1080/08098131.2018.1546223

Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings. Von Bonin D, Klein SD, Würker, Streit E, Avianus O, Grah C, Salomon J and Wolf Ucorresponding author. BioMedCentral. Published online 2018 Jun 25. doi: 10.1186/s13063-018-2727-z. Open access

Arts Therapies for Anxiety, Depression, and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis. Boehm K, Cramer H, Staroszynski T and Ostermann T: Hindawi Publishing Corporation. Evidence-Based Complementary and Alternative Medicine.Volume 2014, Article ID 103297, 9 pages http://dx.doi.org/10.1155/2014/103297

Anthroposophic art therapy in chronic disease: a four-year prospective cohort study. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Explore 2007;3(4):365-71.

Oscillations lf heart rate and respiration synchronize during poetry recitation. Cysarz D, von Bonin D, Lackner H, Heusser P, Moser M, Bettermann H: Am J Physiol Heart Circ Physiol 2004;287:H579-H58

Antroposofinen elämäntapa

Allergic disease and sensitization in Steiner school children. Floistrup H, Swartz J, Bergstrom A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrlander C, Schram-Bijkerk D, Huber M, et al. J Allergy Clin Immunol 2006;117(1):59-66.

Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, et al. Clin Exp Allergy 2005;35(10):1272-1278.

Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study.Schram D, Doekes G, Boeve M, Douwes J, Riedler J, Ublagger E, von Mutius E, Budde J, Pershagen G, Nyberg F, et al. Allergy 2005;60(5):611-618.

An anthroposophic lifestyle and intestinal microflora in infancy. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin, E, Pershagen G, Reinders C, Wreiber K, Scheynius A . Pediatr Allergy Immunol 2002;13(6) :402-11.

Atopy in children of families with an anthroposophic lifestyle. Alm JS, Swartz j, Lilja G, Scheynius A, Pershagen G . Lancet 1999;353(9163) :1485-8.

Perus- ja prekliininen tutkimus

Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model. Steinborn C, Klemd AM, Sanchez- Campillo A-S, Rieger S, Scheffen M, Sauer B, et al. (2017) PLoS ONE 12(7): e0181553. https://doi. org/10.1371/journal.pone.0181553

Aviscumine, a recombinant ribosomal inhibitor, increases the antitumor activity of natural killer cells.Gamerith G, Amann A, Schenk B, Auer T, Lentzen H, Mügge DO, Cima KM, Löffler-Ragg J, Hilbe W, Zwierzina H (2017) Oncology Letters 14 (5), 5563-5568. DOI: 10.3892/ol.2017.686

Synergistic antitumour properties of viscumTT in alveolar rhabdomyosarcoma. Stammer RM, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, Delebinski CI (2017) Journal of Immunology Research 2017. 13 pp. Article ID 4874280. DOI: 10.1155/2017/4874280

Immunomodulatory effects of preparations from anthroposophical medicine for parenteral use.

Gründemann, C.; Diegel, C.; Sauer, B.; Garcia-Käufer, M.; Huber, R. 2015. Immunomodulatory effects of preparations from Anthroposophical Medicine for parenteral use. BMC Complement Altern Med 15: 219. doi:10.1186/s12906-015-0757-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0757-6

 

Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancer-related fatigue? Kröz, M.; Reif, M.; Zerm, R.; Winter, K.; Schad. F.; Gutenbrunner, C.; Girke, M.; Bartsch, C. 2015. Do we have predictors of therapy responsiveness for a multimodal therapy concept and aerobic training in breast cancer survivors with chronic cancerrelated fatigue? Eur J Cancer Care (Engl) 2015; 24(5): 707–717. doi:10.1111/ecc.12278.

https://www.ncbi.nlm.nih.gov/pubmed/25602030

 

Training effect of eurythmy therapy on specific oscillations of heart rate variability. Edelhäuser, F.; Minnerop, A.; Trapp, B.; Büssing, A.; Cysarz, D. 2015. Eurythmy therapy increases specific oscillations of heart rate variability. BMC Complement Altern Med 2015: 167. doi:10.1186/s12906-015-0684-6.

http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0684-6

 

Cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. Schink, M.; Garcia-Käufer, M.; Bertrams, J.; Duckstein, S.M.; Müller, M.B.; Huber, R.; Stintzing, F.C.; Gründemann, C. 2015. Differential cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. J Ethnopharmacol 159: 129–136. doi:10.1016/j.jep.2014.11.003. http://europepmc.org/abstract/med/25446603

 

Cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. Schink, M.; Garcia-Käufer, M.; Bertrams, J.; Duckstein, S.M.; Müller, M.B.; Huber, R.; Stintzing, F.C.; Gründemann, C. 2015. Differential cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. J Ethnopharmacol 159: 129–136. doi:10.1016/j.jep.2014.11.003. http://europepmc.org/abstract/med/25446603

 

Immunomodulatory effects of preparations from anthroposophical medicine for parenteral use. Gründemann, C.; Diegel, C.; Sauer, B.; Garcia-Käufer, M.; Huber, R. 2015. Immunomodulatory effects of preparations from Anthroposophical Medicine for parenteral use. BMC Complement Altern Med 15: 219. doi:10.1186/s12906-015-0757-6. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0757-6 

 

Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy. Hosomi, J.K.; Ghelman, R.; Quintino, M.P.; de Souza, E.; Nakamura, M.; Moron, A.F. 2014. Effects of chronic Bryophyllum pinnatum administration on Wistar rat pregnancy. Forsch Komplementärmed 21(3): 184–189. doi:10.1159/000363709. https://www.karger.com/Article/Pdf/363709

 

Cardio-respiratory balance during day-rest compared to deep sleep, a possible indicator for quality of life.

von Bonin, D.; Grote, V.; Buri, C.; Cysarz, D.; Heusser, P.; Moser, M.; Wolf, U.; Laederach, K. 2014. Adaption of cardio-respiratory balance during day-rest compared to deep sleep – an indicator for quality of life? Psychiatry Res 219 (3): 638–644. https://www.ncbi.nlm.nih.gov/pubmed/25011731

 

Preclinical assays to investigate an anthroposophic pharmaceutical process applied to mistletoe.

Baumgartner, S.; Flückiger, H.; Kunz, M.; Scherr, C.; Urech, K. 2014. Evaluation of Preclinical Assays to Investigate an Anthroposophic Pharmaceutical Process Applied to Mistletoe (Viscum album L.) Extracts. Evid Based Complement Alternat Med 2014: 620974. doi:10.1155/2014/620974. https://www.hindawi.com/journals/ecam/2014/620974/

 

Improvement of circadian rhythm of heart rate variability by eurythmy therapy trainin.

Seifert, G.; Kanitz, J.L.; Pretzer, K.; Henze, G.; Witt, K.; Reulecke, S.; Voss, A. 2013. Improvement of circadian rhythm of heart rate variability by eurythmy therapy training. https://www.ncbi.nlm.nih.gov/pubmed/23533496

 

Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum.

Fürer, K.; Raith, M.; Brenneisen, R.; Mennet, M.; Simoes-Wüst, A.P.; von Mandach, U.; Hamburger, M.; Potterat, O. 2013. Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum, a phytotherapeutic used in obstetrics and gynaecology. Planta Med. 79(16): 1565–1571. doi:10.1055/s-0033-1350808. https://www.ncbi.nlm.nih.gov/pubmed/24072500

 

Impact of colored light on cardiorespiratory coordination. Edelhäuser, F.; Hak, F.; Kleinrath, U.; Lühr, B.;, Matthiessen, P.F.; Weinzirl, J.; Cysarz, D. 2013. Impact of colored light on cardiorespiratory coordination. Evid Based Complement Alternat Med 2013: 810876. doi:10.1155/2013/810876. https://www.hindawi.com/journals/ecam/2013/810876/  

 

Comparative in vitro study of the effects of separate and combined products of Citrus e fructibus and Cydonia e fructibus on immunological parameters of seasonal allergic rhinitis. Baars, E.W.; Jong, M.C.; Boers, I.; Nierop, A.F.; Savelkoul, H.F. 2012. A comparative in vitro study of the effects of separate and combined products of Citrus e fructibus and Cydonia e fructibus on immunological parameters of seasonal allergic rhinitis. Mediators Inflamm. 2012: 109829. doi:10.1155/2012/109829.

https://www.hindawi.com/journals/mi/2012/109829/

 

Inner correspondence and peacefulness among participants in eurythmy therapy and yoga: a validation study.

Büssing, A.; Edelhäuser, F.; Weisskircher, A.; Fouladbakhsh, J.M.; Heusser, P. 2011. Inner Correspondence and Peacefulness with Practices among Participants in Eurythmy Therapy and Yoga: A

Validation Study. Evid Based Complement Alternat Med 2011; pii:329023. doi:10.1155/2011/329023. https://www.hindawi.com/journals/ecam/2011/329023/

 

Homeopathic preparations of quartz, sulfur and copper sulfate assessed by UV-spectroscopy.

 Wolf, U.; Wolf, M.; Heusser, P.; Thurneysen, A.; Baumgartner, S. 2011. Homeopathic Preparations of Quartz, Sulfur and Copper Sulfate Assessed by UV-Spectroscopy. Evid Based Complement Alternat Med 2011: 692798. doi:10.1093/ecam/nep036. https://www.hindawi.com/journals/ecam/2011/692798/

 

Immunomodulatory properties of a lemon-quince preparation as an indicator of anti-allergic potency.

Gründemann, C.; Papagiannopoulos, M.; Lamy, E.; Mersch-Sundermann, V.; Huber, R. 2011. Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. Phytomedicine 18(8–9): 760–768. doi:10.1016/j.phymed.2010.11.016. https://www.ncbi.nlm.nih.gov/pubmed/21256726

Lisätutkimuksia ja julkaisuja kts.myös: Verein für Krebsforschun e.V. Arlesheim (CH) http://www.vfk.ch/l/aktlit80

Kliininen tutkimus (ei misteli)

Satunnaistetut, kontrolloidut tutkimukset

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancerrelated fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design. Kröz M, Reif M, Glinz A, Berger B, Nikolaou A, Zerm R, Brinkhaus B, Girke M, Büssing A, Gutenbrunner C, and On behalf of the CRF-2 study group. BMC Cancer (2017) 17:166. DOI 10.1186/s12885-017-3142-7. Full article Open Access: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335840/

 

Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial.

Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2014. Quality of life of patients with advanced pancreatic cancer during treatment with mistletoe: a randomized controlled trial. Dtsch Ärztebl Int 111(29–30): 493–502. doi:10.3238/arztebl.2014.0493. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150026/

 

Additional therapy with a mistletoe product during adjuvant chemotherapy of breast cancer patients improves quality of life.

Tröger, W.; Ždrale, Z.; Tišma, N.; Matijašević, M. 2014. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evid Based Complement Alternat Med 2014: 430518. doi:10.1155/2014/430518. https://www.hindawi.com/journals/ecam/2014/430518/

 

Mistletoe therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival.

Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. 2013. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomized clinical trial on overall survival. Eur. J. Cancer 49(18): 3788–3797. https://www.ncbi.nlm.nih.gov/pubmed/23890767

 

Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with a mistletoe extract to chemotherapy alone.

Tröger, W.; Ždrale, Z.; Stanković, N.; Matijašević, M. 2012. Fiveyear follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl) 6: 173–180. doi:10.4137/BCBCR.S10558. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493140/

 

Treating menopausal symptoms with a complex anthroposophic remedy or placebo: a randomized controlled trial. von Hagens, C.; Schiller, P.; Godbillon, B.; Osburg, J.; Klose, C.; Limprecht, R.; Strowitzki, T. 2012. Treating menopausal symptoms with a complex remedy or placebo: a randomized controlled trial. Climacteric 15(4): 358–367. doi:10.3109/13697137.2011.597895. https://www.ncbi.nlm.nih.gov/pubmed/22017387

 

Citrus/Cydonia Compositum subcutaneous injections versus nasal spray for seasonal allergic rhinitis: a randomized controlled trial on efficacy and safety.

Baars, E.W.; Jong, M.; Nierop, A.F.; Boers, I.; Savelkoul, H.F. 2011. Citrus/Cydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis: A Randomized Controlled Trial on Efficacy and Safety. ISRN Allergy 2011: 836051. doi:10.5402/2011/836051. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658594/

Ei-satunnaistetut, kontrolloidut tutkimukset ja kohorttitutkimukset

Integrative versus Conventional Therapy of Chronic Otitis Media with Effusion and Adenoid Hypertrophyin Children: A Prospective Observational Study. Szoeke H, Maródi M, Sallay Z, Székely B, Sterner MG and  Hegyi G.: Forsch Komplementmed 2016;23:231–239. DOI: 10.1159/000448440. http://www.karger.com/Article/PDF/448440

 

Targeting inflammation in cancer-related-fatigue: a rationale for mistletoe therapy as supportive care in colorectal cancer patients. Bock, P.R.; Hanisch, J.; Matthes, H.; Zänker, K.S. 2014. Targeting inflammation in cancer-related-fatigue: a rationale for mistletoe therapy as supportive care in colorectal cancer patients. Inflamm Allergy Drug Targets 13(2): 105–111. https://www.ncbi.nlm.nih.gov/pubmed/24766319 

 

Antibiotic use in children with acute respiratory or ear infections in comparison of anthroposophic and conventional treatment under routine primary care conditions. Hamre, H.J.; Glockmann, A.; Schwarz, R.; Riley, D.S.; Baars, E.W.; Kiene, H.; Kienle, G.S. 2014. Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Evid Based Complement Alternat Med 2014: 243801. doi:10.1155/2014/243801. https://www.hindawi.com/journals/ecam/2014/243801/

 

The impact of eurythmy therapy on stress coping strategies and health-related quality of life. Kanitz, J.L.; Pretzer, K.; Reif, M.; Voss, A.; Brand, R.; Warschburger, P.; Längler, A.; Henze, G.; Seifert, G. 2011. The impact of eurythmy therapy on stress coping strategies and health-related quality of life in healthy, moderately stressed adults. Complement Ther Med 19(5): 247–255. doi:10.1016/j.ctim.2011.06.008. https://www.ncbi.nlm.nih.gov/pubmed/21944654

 

Anthroposophic supportive treatment in children with medullo-blastoma receiving first-line therapy. Seifert, G.; Rutkowski, S.; Jesse, P.; Madeleyn, R.; Reif, M.; Henze, G.; Längler, A. 2011. Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy. J. Pediatr. Hematol. Oncol. 33(3): e105–108. doi:10.1097/ MPH.0b013e31820946d3. https://www.ncbi.nlm.nih.gov/pubmed/21368673

Havaintotutkimukset, tapausselostukset ja tapaussarjatutkimukset

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors. Kienle GS, Mussler M, Dieter Fuchs and Kiene H. Evidence-Based Complementary and Alternative Medicine, Volume 2016, Article ID 4628287,

http://dx.doi.org/10.1155/2016/4628287

 

Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer. Axtner J , Steele M, Kröz M, Spahn G, Matthes H and Schad F. BMC Cancer (2016) 16:579 DOI 10.1186/s12885-016-2594-5. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2594-5

 

Effect of Colchicum autumnale in patients with goitre and euthyroidism or mild hyperthyroidism. Scheffer, C.; Debus, M.; Heckmann, C.; Cysarz, D.; Girke, M. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect – Results of an Observational Study. Evid Based Complement Alternat Med 2016: 2541912. doi:10.1155/2016/2541912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756131/

 

Improvement of sleep quality during treatment with Bryophyllum. Simoes-Wüst, A.P.; Hassani, T.A.; Müller-Hübenthal, B.; Pittl, S.; Kuck, A.; Meden, H.; Eberhard, J.; Decker, M.; Fürer, K.; von Mandach, U.; Bryophyllum Collaborative Group. 2015. Sleep Quality Improves During Treatment with Bryophyllum pinnatum: An Observational Study on Cancer Patients. Integr Cancer Ther 2015; 14(5): 452–459. doi:10.1177/1534735415580680. https://www.ncbi.nlm.nih.gov/pubmed/25873294

 

Sleep quality in pregnancy during treatment with Bryophyllum. Lambrigger-Steiner, C.; Simoes-Wüst, A.P.; Kuck, A.; Fürer, K.; Hamburger, M.; von Mandach, U. 2014. Sleep quality in pregnancy during treatment with Bryophyllum pinnatum: an observational st udy. Phytomedicine 21(5): 753–757. doi:10.1016/j. phymed.2013.11.003. https://www.ncbi.nlm.nih.gov/pubmed/24373544

 

Mesembryanthemum crystallinum L. as a dermatologically effective medicinal plant. Raak, C.; Molsberger, F.; Heinrich, U.; Bertram, M.; Ostermann, T. 2014. Mesembryanthemum crystallinum L. as dermatologically effective medicinal plant – first results from 3 pilot studies. Forsch Komplementärmed 21(6): 366–373. doi:10.1159/000369909. https://www.ncbi.nlm.nih.gov/pubmed/25592948

 

Eurythmy therapy in the aftercare of pediatric posterior fossa tumour survivors – a pilot study. Kanitz, J.L.; Pretzer, K.; Calaminus, G.; Wiener, A.; Längler, A.; Henze, G.; Driever, P.H.; Seifert, G. 2013. Eurythmy therapy in the aftercare of pediatric posterior fossa tumour survivors – a pilot study. Complement Ther Med 2013; 21 (Suppl. 1): 3–9. doi:10.1016/j.ctim.2012.02.007. https://www.ncbi.nlm.nih.gov/pubmed/23578915

 

Intratumoral mistletoe therapy in patients with unresectable pancreas carcinoma: a retrospective analysis. Schad, F.; Axtner, J.; Buchwald, D.; Happe, A.; Popp, S.; Kröz, M.; Matthes, H. 2013. Intratumoral Mistletoe (Viscum album L) Therapy in Patients with Unresectable Pancreas Carcinoma: A Retrospective Analysis. Integr Cancer Ther 13(4): 332–340. https://www.ncbi.nlm.nih.gov/pubmed/24363283

 

Effects of eurythmy therapy in the treatment of essential arterial hypertension: a pilot study. Zerm, R.; Lutnas-Mast, F.; Mast, H.; Girke, M.; Kröz, M. 2013. Effects of eurythmy therapy in the treatment of essential arterial hypertension: a pilot study. Glob Adv Health Med 2013; 2(1): 24–30. doi:10.7453/gahmj.2013.2.1.006. Erratum in: Glob Adv Health Med 2013; 2(2): 8. Zerm, Ronald. https://www.ncbi.nlm.nih.gov/pubmed/24381822

 

Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings. Hamre, H.J.; Kiene, H.; Glockmann, A.; Ziegler, R.; Kienle, G.S. 2013. Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings. BMC Res Notes 2013; 6: 269. doi:10.1186/1756-0500-6-269. https://www.ncbi.nlm.nih.gov/pubmed/23849335

 

Improvement of heart rate variability by eurythmy therapy after a 6-week eurythmy therapy training. Seifert, G.; Kanitz, J.L.; Pretzer, K.; Henze, G.; Witt, K.; Reulecke, S.; Voss, A. 2012. Improvement of heart rate variability by eurythmy therapy after a 6-week eurythmy therapy training. Integr Cancer Ther 11(2): 111–119. doi:10.1177/1534735411413263. https://www.ncbi.nlm.nih.gov/pubmed/21733984

 

Pulpa dentis D30 for acute reversible pulpitis: a prospective cohort study in routine dental practice. Hamre, H.J.; Mittag, I.; Glockmann, A.; Kiene, H.; Tröger, W. 2011. Pulpa dentis D30 for acute reversible pulpitis: A prospective cohort study in routine dental practice. Altern Ther Health Med 17(1): 16–21. https://www.ncbi.nlm.nih.gov/pubmed/21614940

 

Influence of self-regulation and autonomic regulation on survival in breast and colon carcinoma patients. Kröz, M.; Reif, M.; Büssing, A.; Zerm, R.; Feder, G.; Bockelbrink, A.; von Laue, H.B.; Matthes, H.; Willich, S.N.; Girke, M. 2011. Does self-regulation and autonomic regulation have an influence on survival in breast and colon carcinoma patients? Results of a prospective outcome study. Health Qual Life Outcomes 2011; 9: 85. doi:10.1186/1477-7525-9-85. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192663/

 

Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Eisenbraun, J.; Scheer, R.; Kröz, M.; Schad, F.; Huber, R. 2011. Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine 18(2–3): 151–157. doi:10.1016/j.phymed.2010.06.013. https://www.ncbi.nlm.nih.gov/pubmed/20724129

 

Improvement of Asthma and Gastroesophageal Reflux Disease With Oral Pulvis stomachicus cum Belladonna, a Combination of Matricaria recutita, Atropa belladonna, Bismuth, and Antimonite: A Pediatric Case Report. von Schoen-Angerer T,  Madeleyn R, Kiene H, Kienle GS, Vagedes J. 2015 http://www.gahmj.com/doi/full/10.7453/gahmj.2015.019

 

Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. Werthmann, P.G.; Helling, D.; Heusser, P.; Kienle, G.S. 2014. Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. BMJ Case Rep 2014; pii:bcr2013203180. doi:10.1136/bcr-2013-203180. http://casereports.bmj.com/content/2014/bcr-2013-203180.abstract

 

Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts. Werthmann, P.G.; Sträter, G.; Friesland, H.; Kienle, G.S. 2013. Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts – a case report. Phytomedicine 20(3–4): 324–327. doi:10.1016/j.phymed.2012.11.001. https://www.ncbi.nlm.nih.gov/pubmed/23394841

 

Facilitating self-healing in anthroposophic psychotherapy. Lees, J. 2013. Facilitating self healing in anthroposophic psychotherapy. Forsch Komplementärmed 20(4): 286–289. doi:10.1159/000354192. https://www.ncbi.nlm.nih.gov/pubmed/24030451

 

Inpatient treatment of community-acquired pneumonias with integrative medicine. Geyer, U.; Diederich, K.; Kusserow, M.; Laubersheimer, A.; Kramer, K. 2013. Inpatient treatment of community-acquired pneumonias with integrative medicine. Evid Based Complement Alternat Med 2013: 578274. doi:10.1155/2013/578274. https://www.hindawi.com/journals/ecam/2013/578274/

 

Eurythmy therapy in anxiety. Kienle, G.S.; Hampton Schwab, J.; Murphy, J.B.; Andersson, P.; Lunde, G.; Kiene, H.; Hamre, H.J. 2011. Eurythmy Therapy in anxiety. Altern Ther Health Med 17(4): 56–63. https://www.ncbi.nlm.nih.gov/pubmed/22314634

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(Päivitetty 6.2.2019)